Herr Philipp Klahn

Chemie

Team

www.oc.uni-wuppertal.de/prof-dr-stefan-f-ki

Biografie

Kurzbiographie:

University education

• Since 10/2010 Doctoral studies (Dr. rer. nat.)
  Bergische Universität Wuppertal (BUW), Wuppertal/Germany (Since 09/2011)
  Technische Universität München (TUM), Garching/Germany (10/2010-09/2010) Advisor: Prof. Dr. Stefan F. Kirsch, Titel: Development of novel stereo- and chemoselective methods for the synthesis of bicyclic compounds, heterocyles and azides and its application to total syntheses
• 10/2008-6/2010 Master of Science (Chemistry)
  Technische Universität München (TUM), Garching/ Germany Master Thesis: Palladium-catalyzed Overman esterification as a central element in asymmetric synthesis (passed with high distinction, 2nd of class 2010)
• 10/2005-07/2008 Bachelor of Science (Chemistry)
  Technische Universität München (TUM), Garching/ Germany Bachelor Thesis: Studies towards the biomimetic total synthesis of Phelligridine A

School education and alternative service

• 09/2002-01/2005 Apprenticeship as laboratory assistant
  ALTANA Pharma AG, (now Nycomed/Takeda AG), Konstanz/ Germany
• 07/1999-09/2002 Alternative Service at department for civil protection and disaster control of the German Red Cross (DRK)
• 09/1993-04/2002 Secondary school, Kaltenkirchen/ Germany Matriculation certificate, specialized courses: chemistry and geography
• 09/1989-07/1993 Primary school, Kaltenkirchen/ Germany
  Employments and internships
• 07/2010-09/2010 Research Internship
  Bayer-Schering Pharma AG (now Bayer Healthcare AG), Berlin/Germany
  Department of Medicinal Chemistry , Advisor: Dr. Hilmar Weinman
  Synthesis of potential anti-androgenic steroid derivatives for fertilization control
• 04/2007-06/2010 Teaching assistant
  Technische Universität München (TUM), Garching/ Germany
• 03/2006-05/2006 Research Internship
• 08/2006-10/2006 4 SC AG, Martinsried/ Germany
• 03/2009-05/2008 Department Lead Validation/ Medicinal Chemistry, Advisor: Dr. Stefan Tasler
• 02/2009-04/2009 Synthesis of potential GPCR-agonists, kinase inhibitors and antiprotozoica
• 01/2005-10/2005 Technician
  ALTANA Pharma AG (now Nycomed/Takeda AG), Konstanz/ Germany Department Lead Finding/ Medicinal Chemistry, Synthesis of potential active compounds as pharmaceuticals
• 04/2000-05/2000 Internship
  Institute for Pathology und Toxicology, Altana Pharma AG (now Nycomed/Takeda AG), Hamburg/Germany

Scholarships and awards

• since 10/2011 Member of the Center for Graduate Studies (CGS) BUW
• since 10/2010 Member of the TUM Graduate School/ Graduate Center of Chemistry (FGCh)
• since 10/2010 Fellow of the Fonds der Chemischen Industrie (FCI)
• 07/2010 Award of the Bayer-Schering Pharma AG for acknowledgement of outstanding performances in the synthesis of novel steroid intermediates in actual projects
• 08/2009 Karl-Ziegler scholarship, Karl-Ziegler foundation/GDCh
• 06/2008 Karl-Oskar-Forster scholarship (TUM)
• 10/2007-09/2010 Fellow of the Hans-Rudolf foundation
• 01/2005 Award for best of class 2005, Kerschensteiner professional school

Titel und Abstract des Dissertationsprojekts:

Development of novel stereo- and chemoselective methods for the synthesis of bicyclic compounds, heterocyles and azides and its application to total syntheses.

Neuigkeiten

Vortragstätigkeit:

• Method development in organic syntheses, P. Klahn Jungchemiker Forum (JFC)/ GDCh, Spring Symposium 2012, Bergische Universität Wuppertal, Wuppertal/Germany, 21.05.2012. (Oral Presentation)
• Practical Azidation of 1,3-Dicarbonyls, P. Klahn, Regional Meeting of Fellows of Fonds der Chemischen Industrie (FCI), TU Dortmund, Dortmund/Germany, 08.12.2011. (Oral Presentation)
• Gold and platinum catalyzed aromatization of 3-siloxy-1,5-enynes, J. T. Binder, B. Crone, A. Duschek, T. T. Haug, P. Klahn, S. F. Kirsch, C. Liébert, H. Menz, GDCh-Wissenschaftsforum Chemie 2009, Frankfurt a. M./ Germany (Poster)

Publikationen:

• Total Synthesis of (+)-Cyperolone, S. F. Kirsch, P. Klahn, A. Duschek, C. Liébert, Org. Lett. 2012, 14, 1250–1253 (Communication)

• Practical Azidation of 1,3-Dicarbonyls, T. Harschneck, S. Hummel, S. F. Kirsch, P. Klahn, Chem. Eur. J. 2011, 18, 1178-1193. (Fullpaper)

• The Use of COP-OAc in the Catalyst-controlled Syntheses of 1,3-Polyols, S. F. Kirsch, P. Klahn, H. Menz, Synthesis 2011, 22, 3592-3603.

• Electronic Fine-Tuning of Carbene Ligands and its Impact on Gold Catalysis, P. Klahn, S. F. Kirsch, ChemCatChem 2011, 3, 649-652.

• Thienopyrimidines as β3-adrenoreceptor agonists: Hit to lead optimization, S. Tasler, R. Baumgartner, A. Ammendola, J. Schachtner, T. Wieber, M. Blisse, S. Rath, M. Zaja, P. Klahn, U. Quotschalla, P.Ney, Bioorg. Med. Chem. Lett. 2010, 20, 6180-6115.

• Gold and platinum catalyzed aromatization of 3-siloxy-1,5-enynes, Poster: GDCh-Wissenschaftsforum Chemie 2009, Frankfurt a. M./ Deutschland

• Gold-catalyzed reactivity of 3-silyloxy-1,5-enynes: a synthetic tool for the synthesis of complex structures and its limitations, H. Menz, J. T. Binder, B. Crone, A. Duschek, T. T. Haug, S. F. Kirsch, P. Klahn, C. Liébert, Tetrahedron 2009, 65, 9, 1880-1888

Sonstige wissenschaftliche Aktivitäten/Mitgliedschaften:

• Mitglied GDCh (Liebig Vereinigung für Organische Chemie, Fachgruppe für Photochemie)
• Mitglied ACS
• Mitglied TUMGS
• Mitglied ZGS Bergische Universität Wuppertal

Sonstiges

M. Sc. Chem. (TUM)